ASYMPTOMATIC PAPILLARY FIBROELASTOMA OF THE AORTIC VALVE IN A YOUNG WOMAN - A CASE REPORT


Renal L-2-hydroxyglutarate dehydrogenase activity promotes hypoxia tolerance and mitochondrial metabolism in Drosophila melanogaster

Objectives: The mitochondrial enzyme L-2-hydroxyglutarate Heart Rate Ring dehydrogenase (L2HGDH) regulates the abundance of L-2-hydroxyglutarate (L-2HG), a potent signaling metabolite capable of influencing chromatin architecture, mitochondrial metabolism, and cell fate decisions.Loss of L2hgdh activity in humans induces ectopic L-2HG accumulation,

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